What do MK4 and MK-7 mean when we use vitamin K2?

2025-08-29

When we talk about the vitamin K family, vitamin K2 often stands out — not only for its role in bone health and cardiovascular hashtagprotection, but also because of the fascinating differences within its own family members.

Two key players are hashtagMK4 (hashtagMenaquinone-4) and hashtagMK7 (Menaquinone-7). On paper they sound similar, but in practice, they’re very different:

👉 VK4 (Menaquinone-4)

Effective dosage: 45 mg/day

Duration: short, needs multiple doses daily

Impact on serum K2: minimal

Source: synthetic only

Absorption: quick

👉 VK7 (Menaquinone-7)

Effective dosage: 45 μg/day (yes, micrograms, not milligrams!)

Duration: long, once a day is enough

Impact on serum K2: 7–8× increase

Source: natto (fermentation) or synthesis

Absorption: quick

🤖 While both are absorbable, VK7 offers a much longer half-life and stronger impact on serum levels, which is why it’s often the preferred choice for supplement formulations today.

I’m curious — in your market or product development experience, do you see more demand for VK4 or VK7?

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